JScreen.org Offers Mail-in Self-Test Genetic Cancer Screening

This new JScreen initiative offers at-home testing for more than 60 cancer susceptibility genes associated with hereditary risks for breast, ovarian, prostate, colorectal, skin and many other cancers. JScreen, www.jscreen.org, a national public health initiative based out of Emory University School of Medicine’s Department of Human Genetics, adds yet another way to save lives with the launch of its CancerGEN testing initiative.  This new JScreen initiative offers at-home testing for…

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BASSER CENTER FOR BRCA – PENN MEDICINE

So wonderful to read through the BASSER Progress report! Gives me such hope for our children’s future. IN 10 YEARS By 2030, Basser will continue to improve our understanding of BRCA, allowing us to overcome chemotherapy resistance, develop new targeted therapies for mutation carriers, and have better medications for managing metastatic breast cancer. We also…

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Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer

Abstract BACKGROUND Poly(adenosine diphosphate–ribose) polymerase inhibitors target cancers with defects in homologous recombination repair by synthetic lethality. New therapies are needed to reduce recurrence in patients with BRCA1 or BRCA2 germline mutation–associated early breast cancer. METHODS We conducted a phase 3, double-blind, randomized trial involving patients with human epidermal growth factor receptor 2 (HER2)–negative early…

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Genetic testing could prevent future health risk for those with family history of cancer

By Madison Pitsch Published: Oct. 20, 2020 at 5:11 PM EDT https://www.1011now.com/2020/10/20/albion-mother-gets-genetic-testing-for-cancer-encourages-others-at-risk-to-do-so/ LINCOLN, Neb. (KOLN) -October is Breast Cancer Awareness Month. For those who are facing a family history of cancer diagnoses, there is a way to learn more about your own risks for cancer. Genetic testing, for people at high risk of cancer, can change the…

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BRCA1 cancer CRISPR disease & medicine genetics & genomics News

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR. Sukanya Charuchandra Nearly 4,000 genetic variants of BRCA1, a tumor-suppressing gene whose loss of function can lead to breast and ovarian cancer, have been functionally classified, according to a study published September 12 in Nature. These findings could help with ascribing cancer risk to…

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US Preventive Services Task Force updates BRCA related cancer: Risk Assessment, Genetic Counseling, and Genetic Testing:

The US Preventive Services Task Force (USPSTF) updated its 2013 recommendation on risk assessment, genetic counseling, and genetic testing for BRCA-related cancer. The US Preventive Services Task Force (USPSTF) makes recommendations about the effectiveness of specific preventive care services for patients without obvious related signs or symptoms. To update its 2013 recommendation, the USPSTF commissioned a…

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